During my test runs for a challenge, where I would use only knife for a solo lethal play through, I encountered an issue - using ONLY a knife (no gun-strikes and no firearm support) several times my inputs would begin to bug out and stop working, especially ones that were connected with animations. Sometimes the game would not allow a stim pack to be applied, sometimes the running animation would not work, sometimes parry stops working for several inputs. It also stops being possible to parry immediately after getting up from the ground. On rarer occasions, Zoanthropes begin to teleport closer to the player; while Ravenors go into charge attack apply damage to the player, even if there is a wall separating them. Found remedies that fix the bug: entering aim, a gun-strike, glory kill (rarely). 

On ranged weapons, as you can imagine, I did not see these bugs occurring.